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Rectal administration of medication may be performed with any of the following: A suppository, a solid drug delivery system inserted into the rectum, where it dissolves or melts to exert local or systemic effects. A micro-enema, a small amount (usually less than 10 millilitres) of a liquid-drug solution injected into the rectum.
Dantron is a stimulant drug and stool softener [31] used alone or in combinations in enemas. [32] Considered to be a carcinogen [ 33 ] its use is limited, e.g., restricted in the UK to patients who already have a diagnosis of terminal cancer and not used at all in the USA .
Lactulose is a non-absorbable sugar used in the treatment of constipation and hepatic encephalopathy. [3] [4] It is administered orally for constipation, and either orally or rectally for hepatic encephalopathy. [3] It generally begins working after 8–12 hours, but may take up to 2 days to improve constipation. [1] [2]
Oral administration of a liquid. In pharmacology and toxicology, a route of administration is the way by which a drug, fluid, poison, or other substance is taken into the body. [1] Routes of administration are generally classified by the location at which the substance is applied. Common examples include oral and intravenous administration ...
Orally administered sodium picosulfate is generally used for thorough evacuation of the bowel, usually for patients who are preparing to undergo a colonoscopy. It takes 12–24 hours to work, since it works in the colon. [3] Abdominal cramps and diarrhea are normal effects of picosulfate and should be expected.
Bisacodyl is an organic compound that is used as a stimulant laxative drug. It works directly on the colon to produce a bowel movement. It is typically prescribed for relief of episodic and chronic constipation and for the management of neurogenic bowel dysfunction, as well as part of bowel preparation before medical examinations, such as for a colonoscopy.
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