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Viral cardiomyopathy occurs when viral infections cause myocarditis with a resulting thickening of the myocardium and dilation of the ventricles. These viruses include Coxsackie B and adenovirus, echoviruses, influenza H1N1, Epstein–Barr virus, rubella (German measles virus), varicella (chickenpox virus), mumps, measles, parvoviruses, yellow fever, dengue fever, polio, rabies, and the ...
Myocarditis can progress to inflammatory cardiomyopathy when there are associated ventricular remodeling and cardiac dysfunction due to chronic inflammation. [ 6 ] [ 7 ] Symptoms can include shortness of breath , chest pain , decreased ability to exercise , and an irregular heartbeat . [ 1 ]
Beaches (the working title as Remember Me) is a 1988 American comedy-drama film adapted by Mary Agnes Donoghue and based on Iris Rainer Dart's 1985 novel of the same name. It was directed by Garry Marshall , and stars Bette Midler , Barbara Hershey , Mayim Bialik , John Heard , James Read , Spalding Gray , and Lainie Kazan .
Viral-induced dilated cardiomyopathy can be characterized using different methods. A 2011 study showed in coxsackievirus infected heart proteome , increased levels of fibrotic extracellular matrix proteins and reduced amounts of energy-producing enzymes can be observed suggesting they could be characteristic in enteroviral cardiomyopathy.
Coxsackie B is a group of six serotypes of coxsackievirus (CVB1-CVB6), a pathogenic enterovirus, that trigger illness ranging from gastrointestinal distress to full-fledged pericarditis and myocarditis (coxsackievirus-induced cardiomyopathy). [1] [2] The genome of Coxsackie B virus consists of approximately 7,400 base pairs. [3]
In 2015 cardiomyopathy and myocarditis affected 2.5 million people. [6] Hypertrophic cardiomyopathy affects about 1 in 500 people while dilated cardiomyopathy affects 1 in 2,500. [3] [10] They resulted in 354,000 deaths up from 294,000 in 1990. [7] [11] Arrhythmogenic right ventricular dysplasia is more common in young people. [2]
Cardiomyopathy is a disease of the heart muscle that make it larger or stiffer, sometimes making the heart worse at pumping blood. [16] Specialization of general cardiology to just that of the cardiomyopathies leads to also specializing in heart transplant and pulmonary hypertension .
Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription is the method of transcription. Translation takes place by −1 ribosomal frameshifting, viral initiation, and ribosomal skipping. The virus exits the host cell by lysis, and viroporins. Human and vertebrates serve as the natural host.