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Misoprostol is used for the prevention of NSAID-induced gastric ulcers.It acts upon gastric parietal cells, inhibiting the secretion of gastric acid by G-protein coupled receptor-mediated inhibition of adenylate cyclase, which leads to decreased intracellular cyclic AMP levels and decreased proton pump activity at the apical surface of the parietal cell.
Prostaglandin analogues such as misoprostol are used in treatment of duodenal and gastric ulcers. [2] Misoprostol and other prostaglandin analogues protect the lining of the gastrointestinal tract from harmful stomach acid and are especially indicated for the elderly on continuous doses of NSAIDs.
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. [6] [4] [1] [7] It is a mixture of the sodium salts of estrogen conjugates found in horses, such as estrone sulfate and ...
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Equine gastric ulcer syndrome (EGUS) is a common cause of colic and decreased performance in horses. Horses form ulcers in the mucosa of the stomach, leading to pain, decreased appetite, weight loss, and behavioral changes. Treatment generally involves reducing acid production of the stomach and dietary management.
Diclofenac/misoprostol, sold under the brand name Arthrotec, is a fixed-dose combination medication that contains: Diclofenac sodium: Nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties
Common abortifacients used in performing medical abortions include mifepristone, which is typically used in conjunction with misoprostol in a two-step approach. [3] Synthetic oxytocin , which is routinely used safely during term labor , is also commonly used to induce abortion in the second or third trimester .
Mifepristone combined with misoprostol is the preferred medication regimen for management of early pregnancy loss. While misoprostol alone can be used, the addition of a dose of mifepristone twenty-four hours before misoprostol administration improves treatment efficacy. [30]
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