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Rodenticides are chemicals made and sold for the purpose of killing rodents. While commonly referred to as "rat poison", rodenticides are also used to kill mice, woodchucks, chipmunks, porcupines, nutria, beavers, [1] and voles. [2] Some rodenticides are lethal after one exposure while others require more than one.
Similar to other rodenticides, the preparation requires 3–7 days to be effective. Rather than killing rodents through internal haemorrhaging as anticoagulants do, [9] PCC affects a rodent’s digestive system, causing acute dehydration due to its extremely absorptive nature (corn cob has been used in applications such as oil spills in water bodies, seed drying and de-icing). [10]
Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison.In recent years, it has become one of the world's most widely used pesticides.It is typically used as a rodenticide, but is also used to control larger pests such as possums.
Difethialone is an anticoagulant used as a rodenticide. [1] It is considered a second generation agent. [2] In May 2008, the EPA added restrictions on the sale of difethialone in consumer-use rodenticide products and also for exterior use by commercial applicators. [3] [4]
Chlorophacinone is a first-generation anticoagulant rodenticide. The mechanism of action results in internal bleeding due to non-functional clotting factors. It was used as a toxin to control rodent populations.
In most countries, pesticides must be approved for sale and use by a government agency. [5] In the US, EPA is responsible for regulating pesticides under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and the Food Quality Protection Act (FQPA). [6]
Norbormide (Raticate, Shoxin) is a toxic compound used as a rodenticide.It has several mechanisms of action, acting as a vasoconstrictor and calcium channel blocker, [1] but is selectively toxic to rats and has relatively low toxicity to other species, due to a species specific action of opening the permeability transition pores in rat mitochondria.
Tetramethylenedisulfotetramine (TETS) is an organic compound used as a rodenticide (rat poison). [2] It is an odorless, tasteless white powder that is slightly soluble in water, DMSO and acetone, and insoluble in methanol and ethanol.
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