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Antileukemic drugs, anticancer drugs that are used to treat one or more types of leukemia, include: [1]. 6-Mercaptopurine; 6-Thioguanine; Arsenic trioxide; Asparaginase; Cladribine ...
Many different anti-cancer drugs are effective for the treatment of AML. Treatments vary somewhat according to the age of the person and according to the specific subtype of AML. Overall, the strategy is to control bone marrow and systemic (whole-body) disease, while offering specific treatment for the central nervous system (CNS), if involved ...
The widely available medicinal treatments for subleukemic leukemia are the same as widespread recommendations for leukemia such as chemotherapy, radiation therapy, stem cell therapy, and medication. Leukemia treatments typically have three objectives: immediate patient support and relief, future infection prevention, and elimination of the ...
Ehrlich was not optimistic that effective chemotherapy drugs would be found for the treatment of cancer. [194] The first modern chemotherapeutic agent was arsphenamine, an arsenic compound discovered in 1907 and used to treat syphilis. [195] This was later followed by sulfonamides (sulfa drugs) and penicillin.
The most appropriate treatment is based on the individual's age, physical condition, and whether they have the del(17p) or TP53 mutation. [14] As of 2024, the recommended first-line treatments include: Bruton tyrosine kinase inhibitors , such as such as ibrutinib, zanubrutinib, and acalabrutinib
Additional treatments such as Chimeric antigen receptor T cell immunotherapy are being used and further studied. [2] Acute lymphoblastic leukemia affected about 876,000 people globally in 2015 and resulted in about 111,000 deaths. [14] [10] It occurs most commonly in children, particularly those between the ages of two and five.
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations. In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy. The majority of drugs used in cancer chemotherapy are cytostatic, many via ...
Likewise it is a CYP3A4, CYP2D6 and CYP2C9 inhibitor and hence concurrent treatment with substrates of any of these enzymes may increase plasma concentrations of said drugs. [26] Since imatinib is mainly metabolised via the liver enzyme CYP3A4, substances influencing the activity of this enzyme change the plasma concentration of the drug.