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  2. Periventricular leukomalacia - Wikipedia

    en.wikipedia.org/wiki/Periventricular_leukomalacia

    Periventricular leukomalacia (PVL) is a form of white-matter brain injury, characterized by the necrosis (more often coagulation) of white matter near the lateral ventricles. [ 1 ] [ 2 ] It can affect newborns and (less commonly) fetuses; premature infants are at the greatest risk of neonatal encephalopathy which may lead to this condition.

  3. 7+3 (chemotherapy) - Wikipedia

    en.wikipedia.org/wiki/7+3_(chemotherapy)

    "7+3" in the context of chemotherapy is an acronym for a chemotherapy regimen that is most often used today (as of 2014) as first-line induction therapy (to induce remission) in acute myelogenous leukemia, [1] [2] excluding the acute promyelocytic leukemia form, which is better treated with ATRA and/or arsenic trioxide and requires less chemotherapy (if requires it at all, which is not always ...

  4. Leukemia - Wikipedia

    en.wikipedia.org/wiki/Leukemia

    Treatment may involve some combination of chemotherapy, radiation therapy, targeted therapy, and bone marrow transplant, with supportive and palliative care provided as needed. [3] [6] Certain types of leukemia may be managed with watchful waiting. [3] The success of treatment depends on the type of leukemia and the age of the person.

  5. T-cell prolymphocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/T-cell_prolymphocytic_leukemia

    T-cell-prolymphocytic leukemia (T-PLL) is a mature T-cell leukemia with aggressive behavior and predilection for blood, bone marrow, lymph nodes, liver, spleen, and skin involvement. [1] T-PLL is a very rare leukemia, primarily affecting adults over the age of 30. It represents 2% of all small lymphocytic leukemias in adults. [2]

  6. Mercaptopurine - Wikipedia

    en.wikipedia.org/wiki/Mercaptopurine

    Mercaptopurine (6-MP), sold under the brand name Purinethol among others, is a medication used for cancer and autoimmune diseases. [2] Specifically it is used to treat acute lymphocytic leukemia (ALL), acute promyelocytic leukemia (APL), Crohn's disease, and ulcerative colitis.

  7. Adult T-cell leukemia/lymphoma - Wikipedia

    en.wikipedia.org/wiki/Adult_T-cell_leukemia/lymphoma

    Adult T-cell leukemia/lymphoma (ATL or ATLL) is a rare cancer of the immune system's T-cells [1] [2] [3] caused by human T cell leukemia/lymphotropic virus type 1 . [4] All ATL cells contain integrated HTLV-1 provirus further supporting that causal role of the virus in the cause of the neoplasm. [ 4 ]

  8. Chronic myelomonocytic leukemia - Wikipedia

    en.wikipedia.org/.../Chronic_myelomonocytic_leukemia

    [4] [10] [12] Decitabine/cedazuridine (Inqovi) is a fixed-dosed combination medication for the treatment of adults with myelodysplastic syndromes (MDS) and chronic myelomonocytic leukemia (CMML) that was approved for use in the United States in July 2020. [27] Hematopoietic stem cell transplantation remains the only curative treatment for CMML ...

  9. Acute promyelocytic leukemia - Wikipedia

    en.wikipedia.org/wiki/Acute_promyelocytic_leukemia

    Acute promyelocytic leukemia is characterized by a chromosomal translocation involving the retinoic acid receptor alpha (RARA) gene on chromosome 17. [3] In 95% of cases of APL, the RARA gene on chromosome 17 is involved in a reciprocal translocation with the promyelocytic leukemia gene (PML) on chromosome 15, a translocation denoted as t(15;17)(q22;q21). [3]

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