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[4] [5] The gel Leppin Squeezy was distributed at the Hawaii Ironman Triathlon in 1988. Once considered a "cult product in clear packaging", energy gel products are now marketed in fancy packaging [6] and come in a variety of flavors. [3] The energy gel market grew during the 1990s, as professional athletes began endorsing products.
Consistency and viscosity affect the adhesion and retention property of the gel, and are important in ensuring the gel is retained at the site of application and effective delivery of the drug. [ 3 ] The ingredients in topical gel formulation can be broadly categorized into four types: gelator, solvent, drug, and excipients.
Testosterone is a medication and naturally occurring steroid hormone. [9] It is used to treat male hypogonadism, gender dysphoria, and certain types of breast cancer. [9] [10] It may also be used to increase athletic ability in the form of doping. [9]
Penis enlargement, or male enhancement, is any technique aimed to increase the size of a human penis. Some methods aim to increase total length, others the shaft's girth, and yet others the glans and foreskin size. [1] Techniques include surgery, supplements, ointments, patches, and physical methods like pumping, jelqing, and traction. [1]
Warhammer 40,000: Mechanicus is the first video game to feature the Adeptus Mechanicus, a faction of cybernetically enhanced warrior priests. [1] [2] The game features turn-based tactical combat in the style of the XCOM series. [2] Cognition points (CP) dictate how many actions characters can take on their turn. [1]
Applying cream or gel containing testosterone directly to the clitoris, rather than injecting it (the usual route of administration for transgender hormone therapy), lessens systemic absorption, and may be sufficient for those looking only to have a larger clitoris and avoid other unwanted virilizing effects.
Penetration enhancers have been applied to improve the absorption of poorly permeable, hydrophilic drugs or macromolecules. [10] Permeation enhancers that have been used successfully for oral drug development include medium-chain fatty acids like caprylic acid [ 11 ] or caprate, or its amino acid ester like Salcaprozate sodium (SNAC). [ 12 ]
Potato starch slurry Roux. A thickening agent or thickener is a substance which can increase the viscosity of a liquid without substantially changing its other properties. Edible thickeners are commonly used to thicken sauces, soups, and puddings without altering their taste; thickeners are also used in paints, inks, explosives, and cosmetics.