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In the European Randomized Study of Screening for Prostate Cancer (ERSPC) initiated in the early 1990s, the researchers concluded that PSA-based screening did reduce the rate of death from prostate cancer but created a high risk of overdiagnosis, i.e., 1410 men would need to be screened and 48 additional cases of prostate cancer would need to ...
Recognizing that these men differ from those diagnosed today with PSA screening, the cumulative incidence of death from prostate cancer was 20.7% in the untreated group overall, and 11% for men with low risk disease (PSA below 10 ng/ml and Gleason score below 7) - similar to the cumulative incidence of death from prostate cancer of 12.3% at 30 ...
PFS is widely used as a surrogate endpoint in oncology. [4] The definition of "progression" generally involves imaging techniques (plain radiograms, CT scans, MRI, PET scans, ultrasounds) or other aspects: biochemical progression may be defined on the basis of an increase in a tumor marker (such as CA125 for epithelial ovarian cancer or PSA for prostate cancer).
An AI death calculator can now tell you when you’ll die — and it’s eerily accurate. The tool, called Life2vec, can predict life expectancy based on its study of data from 6 million Danish ...
The equation does not define a survival proportion but simply describes the relationships between disease-specific death (excess hazard) rates, background mortality rates (expected death rate) and the overall observed mortality rates. The excess hazard rate is related to relative survival, just as hazard rates are related to overall survival.
Crude mortality rate refers to the number of deaths over a given period divided by the person-years lived by the population over that period. It is usually expressed in units of deaths per 1,000 individuals per year. The list is based on CIA World Factbook 2023 estimates, unless indicated otherwise.
Prostate cancer staging is the process by which physicians categorize the risk of cancer having spread beyond the prostate, or equivalently, the probability of being cured with local therapies such as surgery or radiation.
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
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