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Botulism can occur in many vertebrates and invertebrates. Botulism has been reported in such species as rats, mice, chicken, frogs, toads, goldfish, aplysia, squid, crayfish, drosophila and leeches. [95] Death from botulism is common in waterfowl; an estimated 10,000 to 100,000 birds die of botulism annually. The disease is commonly called ...
Botulinum toxin can cause botulism, a severe flaccid paralytic disease in humans and other animals, [3] and is the most potent toxin known to science, natural or synthetic, with a lethal dose of 1.3–2.1 ng/kg in humans. [4] [5]
The main species responsible for disease in humans are: [15] Clostridium botulinum can produce botulinum toxin in food or wounds and can cause botulism. This same toxin is known as Botox and is used in cosmetic surgery to paralyze facial muscles to reduce the signs of aging; it also has numerous other therapeutic uses.
Methanol has a moderate to high toxicity in humans. As little as 10 mL of pure methanol when drunk is metabolized into formic acid , which can cause permanent blindness by destruction of the optic nerve . 15 mL is potentially fatal, [ 1 ] although the median lethal dose is typically 100 mL (3.4 fl oz) (i.e. 1–2 mL/kg body weight of pure ...
Alcohol inhalation is a method of administering alcohol directly into the respiratory system, with aid of a vaporizing or nebulizing device or bag. It is chiefly applied for recreational use, when it is also referred to as alcohol smoking, but it has medical applications for testing on laboratory rats, and treatment of pulmonary edema and viral pneumonia.
Botulinum toxin, or botulinum neurotoxin (commonly called botox), is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. [24] It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. [25]
Methanol is a toxic alcohol to humans via ingestion due to metabolism. If as little as 10 ml of pure methanol is ingested, for example, it can break down into formic acid , which can cause permanent blindness by destruction of the optic nerve , and 30 ml is potentially fatal, [ 2 ] although the median lethal dose is typically 100 ml (3.4 fl oz ...
The T-2 toxin was an outbreak and made humans develop symptoms like food poisoning, chills, nausea, dizziness, etc. [38] The trichothecenes mycotoxin affects animals by decreasing plasma glucose, red blood cell and leukocyte counts. [38] Pathological changes in the liver and stomach, as well as weight loss has been accounted for. [38]