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  2. Winters's formula - Wikipedia

    en.wikipedia.org/wiki/Winters's_formula

    One difficulty in evaluation acid-base derangements is the presence of multiple pathologies. A patient may present with a metabolic acidosis process alone, but they may also have a concomitant respiratory acidosis. Winters's formula gives an expected value for the patient's P CO 2; the patient's actual (measured) P CO 2 is then compared to this ...

  3. Respiratory compensation - Wikipedia

    en.wikipedia.org/wiki/Respiratory_compensation

    The amount of respiratory compensation in metabolic acidosis can be estimated using Winters' formula. [2] Hyperventilation due to the compensation for metabolic acidosis persists for 24 to 48 hours after correction of the acidosis, and can lead to respiratory alkalosis. [3] This compensation process can occur within minutes. [4]

  4. Metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/Metabolic_acidosis

    Metabolic acidosis has three main root causes: increased acid production, loss of bicarbonate, and a reduced ability of the kidneys to excrete excess acids. [5] Metabolic acidosis can lead to acidemia, which is defined as arterial blood pH that is lower than 7.35. [6]

  5. Delta ratio - Wikipedia

    en.wikipedia.org/wiki/Delta_Ratio

    When this happens the numerator is large, the denominator is small, and the result is a delta ratio which is high (>2). This means a combined high anion gap metabolic acidosis and a pre-existing either respiratory acidosis or metabolic alkalosis (causing the high bicarbonate) – i.e. a mixed acid–base metabolic acidosis. [citation needed]

  6. Anion gap - Wikipedia

    en.wikipedia.org/wiki/Anion_gap

    The magnitude of this difference (i.e., "gap") in the serum is calculated to identify metabolic acidosis. If the gap is greater than normal, then high anion gap metabolic acidosis is diagnosed. The term "anion gap" usually implies "serum anion gap", but the urine anion gap is also a clinically useful measure. [4] [5] [6] [7]

  7. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    Lactic acidosis refers to the process leading to the production of lactate by anaerobic metabolism. It increases hydrogen ion concentration tending to the state of acidemia or low pH . The result can be detected with high levels of lactate and low levels of bicarbonate .

  8. US bird flu response disrupted in early weeks of Trump ... - AOL

    www.aol.com/news/us-bird-flu-response-disrupted...

    The Trump administration has disrupted the U.S. response to bird flu as the outbreak worsens, leading to confusion and concern among federal staff, state officials, veterinarians and health ...

  9. High anion gap metabolic acidosis - Wikipedia

    en.wikipedia.org/wiki/High_anion_gap_metabolic...

    High anion gap metabolic acidosis is a form of metabolic acidosis characterized by a high anion gap (a medical value based on the concentrations of ions in a patient's serum). Metabolic acidosis occurs when the body produces too much acid, or when the kidneys are not removing enough acid from the body. Several types of metabolic acidosis occur ...