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Sulforaphane (sometimes sulphoraphane in British English) is a compound within the isothiocyanate group of organosulfur compounds. [1] It is produced when the enzyme myrosinase transforms glucoraphanin, a glucosinolate, into sulforaphane upon damage to the plant (such as from chewing or chopping during food preparation), which allows the two compounds to mix and react.
Sulforaphane and other isothiocyanates have been studied for their potential biological effects. [3] The isothiocyanates formed from glucosinolates are under laboratory research to assess the expression and activation of enzymes that metabolize xenobiotics , such as carcinogens . [ 3 ]
Extracts from Camptotheca (the "happy tree" or "cancer tree") were used to develop the chemotherapeutic drug Topotecan. Plant sources of anti-cancer agents are plants, the derivatives of which have been shown to be usable for the treatment or prevention of cancer in humans. [1] [2]
This work led to the isolation of sulforaphane, found in broccoli, as a potent inducer of detoxifying phase two enzymes. These findings, published in 1992, [ 4 ] attracted worldwide attention as a major breakthrough in understanding the link between cruciferous vegetable consumption and reduced cancer risk.
Put in his own words, "the prime cause of cancer is the replacement of the respiration of oxygen in normal body cells by a fermentation of sugar." [ 7 ] The body often kills damaged cells by apoptosis , a mechanism of self-destruction that involves mitochondria, but this mechanism fails in cancer cells where the mitochondria are shut down.
A professor with the University of Texas at San Antonio has created a new method to kill cancer cells that are traditionally difficult to eradicate.
An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (C n H 2n+1) to DNA. [1] Since cancer cells, in general, proliferate faster and with less error-correcting than healthy cells, cancer cells are more sensitive to DNA damage—such as being alkylated. Alkylating agents are used to ...
A teen who created a soap that could "transform skin cancer treatment" was chosen as the 2024 Kid of the Year by Time magazine and Time for Kids.. Heman Bekele from Annandale, Virginia, is a 15 ...