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The number of PBA episodes (laughing, crying or aggressive outbursts) were 47% and 49% lower (based on the trial's outcome measures), respectively, for the drug-combination options than for the placebo. The "mean CNS-LS scores" decreased by 8.2 points for both drug-combination options, vs a decrease of 5.7 points for the placebo.
[135] [138] [139] For those patients with MS who have pseudobulbar affect (PBA), characterized by uncontrollable episodes of crying and/or laughing, or other emotional displays, Dextromethorphan/quinidine can be considered as treatment as it is the only FDA approved drug for treatment for PBA, though other medications such as selective ...
SSRI or SNRI medications; As explained in a 2008 study, in people with mood disorders there is a dynamic link between their mood and the way they move. [6] People showing signs of psychomotor agitation may be experiencing mental tension and anxiety, which comes out physically as: fast or repetitive movements; movements that have no purpose
Generalized anxiety disorder (GAD) is an anxiety disorder characterized by excessive, uncontrollable and often irrational worry about events or activities. [5] Worry often interferes with daily functioning, and individuals with GAD are often overly concerned about everyday matters such as health, finances, death, family, relationship concerns, or work difficulties.
While cognitive behavioral therapy is the most widely prescribed treatment for such psychiatric disorders, a commonly prescribed psychotherapeutic treatment for emotional dysregulation is dialectical behavioral therapy, a psychotherapy which promotes the use of mindfulness, a concept called dialectics, and emphasis on the importance of ...
Potential triggers of emotional lability include excessive tiredness, stress or anxiety, overstimulated senses (too much noise, being in large crowds, etc.), being around others exhibiting strong emotions, very sad or funny situations (such as jokes, movies, certain stories or books), death of a loved one, or other situations that elicit stress ...
The Pediatric Anesthetic Emergence Delirium (PAED) scale or the Cornell Assessment of Pediatric Delirium may be used to measure the severity of this condition in children. [2] [3] In this patient population, emergence delirium is typically identified within the first 30 minutes of recovery from anesthesia.
In rare susceptible individuals, midazolam has been known to cause a paradoxical reaction, a well-documented complication with benzodiazepines. When this occurs, the individual may experience anxiety, involuntary movements, aggressive or violent behavior, uncontrollable crying or verbalization, and other similar effects.