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Not all women with PCOS have difficulty becoming pregnant. For those who do, anovulation is a common cause. The mechanism of this anovulation is uncertain, but there is evidence of arrested antral follicle development, which, in turn, may be caused by abnormal interaction of insulin and luteinizing hormone (LH) on granulosa cells.
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom, and not the underlying cause of the disorder.
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According to a press announcement in July 2023, a daily hormonal oral contraceptive was first made accessible to the public without a prescription. [165] Although this drug class was approved for prescription use as early as in 1973, it took an additional 50 years to de-escalate its legal status.
Acrobat Messenger is a document utility for Acrobat users that was released by Adobe Systems in 2000 to convert paper documents into PDF files that can be e-mailed, faxed, or shared online. Acrobat Reader Touch is a free PDF document viewer developed and released on December 11, 2012, by Adobe Systems for the Windows Touch user interface.
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Apache OpenOffice from version 3.0 can import Office Open XML files but not save them. [46] Version 3.2 improved this feature with read support even for password-protected Office Open XML files. [47] [48] [49] The Go-oo fork of OpenOffice could also write OOXML files. KOffice from version 2.2 and later was able to import OOXML files.
CpG motifs are considered pathogen-associated molecular patterns due to their abundance in microbial genomes but their rarity in vertebrate genomes. [2] The CpG PAMP is recognized by the pattern recognition receptor ( PRR ) Toll-Like Receptor 9 ( TLR9 ), which is constitutively expressed only in B cells and plasmacytoid dendritic cells (pDCs ...