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4-Aminophenol is a building block used in organic chemistry. Prominently, it is the final intermediate in the industrial synthesis of paracetamol. Treating 4-aminophenol with acetic anhydride gives paracetamol: [8] [9] [10] It is a precursor to amodiaquine, mesalazine, AM404, parapropamol, B-86810 & B-87836 (c.f. WO 2001042204 ).
The three aminophenol isomers: Left: 2-Aminophenol (o-aminophenol) Center: 3-Aminophenol (m-aminophenol) Right: 4-Aminophenol (p-aminophenol) Aminophenol may refer to any of three isomeric chemical compounds: 2-Aminophenol; 3-Aminophenol; 4-Aminophenol; They are simultaneously an aniline and a phenol
Substance Formula 0 °C 10 °C 20 °C 30 °C 40 °C 50 °C 60 °C 70 °C 80 °C 90 °C 100 °C Barium acetate: Ba(C 2 H 3 O 2) 2: 58.8: 62: 72: 75: 78.5: 77: 75
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2-Aminophenol is an organic compound with the formula C 6 H 7 NO. Along with its isomer 4-aminophenol , it is an amphoteric molecule and a reducing agent . It is a useful reagent for the synthesis of dyes and heterocyclic compounds . [ 3 ]
However, this synthesis risks the self-condensation of alcohol itself (e.g. ethanol self-condenses to form diethyl ether). A more common and higher-yielding reaction is the Williamson ether synthesis , where a phenol is converted by a strong base to the phenoxide ion, which can subsequently be reacted with an alkyl halide via nucleophilic ...
3-Aminophenol is an organic compound with formula C 6 H 4 (NH 2)(OH). It is an aromatic amine and a phenol . It is the meta isomer of 2-aminophenol and 4-aminophenol .
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