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The infectious dose is 1000–10,000 bacteria (although ten to five hundred bacteria can be enough to infect humans). Campylobacter species are sensitive to hydrochloric acid in the stomach, and acid reduction treatment can reduce the amount of inoculum needed to cause disease. [citation needed]
Other known sources of Campylobacter infections include food products, such as unpasteurised milk and contaminated fresh produce. [6] The infectious dose of Campylobacter ranges between 1000 and 10,000, but even 500–800 colony forming units (CFU) has also been reported to cause disease. The bacteria can also be transmitted to humans via ...
[citation needed] Campylobacter has, on rare occasions, been suggested to cause hemolytic uremic syndrome [32] and thrombotic thrombocytopenic purpura, [33] though no unequivocal case reports exist. Campylobacter infection is the most common trigger of Guillain–Barré syndrome. [34] Gastrointestinal perforation is a rare complication of ileal ...
To compare the dose-response relationships for different effects caused by the same bacterium, or for the same effect caused by different bacteria, one can directly compare the values of r; also, it can be used to evaluate the efficacy of a drugs such as antibiotics. [5]
Campylobacter upsaliensis infections in humans can cause Campylobacteriosis, a more significant gastroenteritis. [3] C. upsaliensis is the second most common Campylobacter species isolated in humans with diarrhea (behind Campylobacter jejuni). [3] Clinical signs include fever, diarrhea (sometimes bloody), and stomach cramps. [19]
In the United States, the highest incidence of Campylobacter infection in 2010 was in children younger than 5 years and was 24.4 cases per 100,000 population. [52] Community based studies done in developing countries show about 60,000 out of every 100,000 children under five years old are affected by campylobacter infections. [3]
The usual dose by mouth is one capsule of 250 mg 4 times a day in adults and half the adult dose as a syrup for children under the age of 10 years but over 2. [4] For children below the age of 2 years, the oral dose is a quarter of the adult oral dose. [3] Ampicillin/flucloxacillin is taken orally about half an hour before food. [5]
[1] [2] [4] [5] While tylosin may be one appropriate therapeutic choice in theory for the conditions listed above, many other antibiotics may be preferable for treating a specific infection, and tylosin will not be the first choice. It is also used as a growth promoter for a variety of terrestrial and aquatic animals grown for human consumption ...