Search results
Results from the WOW.Com Content Network
Articular cartilage stem cell paste grafting was initially described by Kevin R. Stone M.D., a San Francisco-based orthopedic surgeon, in 1997 . The technique was devised in response to reports that many of the contemporary cartilage restoration procedures lead to the development of fibrocartilage, not true hyaline articular cartilage. Knowing ...
Autograft, tissue transplanted from one site to another on the same patient. An autograft reduces the risk of rejection but requires a second surgery site, adding pain, risk and possible longer aftercare. Xenograft, a transplant from another species; Isograft, a transplant from a genetically identical donor, such as an identical twin.
Kidney autotransplantation is a method of a nephron-sparing renal tumor excision or complex renal artery aneurysm management. [ 9 ] [ 10 ] The uses of ex vivo surgery followed by autotransplantation were reported also for heart, lungs and intestines, including multivisceral approaches.
This short-term solution is not considered as an articular cartilage repair procedure but rather a palliative treatment to reduce pain, mechanical restriction and inflammation. Lavage focuses on removing degenerative articular cartilage flaps and fibrous tissue. The main target groups are patients with very small defects of the articular cartilage.
Immune privilege is also believed to occur to some extent or able to be induced in articular cartilage. [ 2 ] [ 3 ] [ 4 ] This was once thought to also include the brain , but this is now known to be incorrect, as it has been shown that immune cells of the central nervous system contribute to the maintenance of neurogenesis and spatial learning ...
An articular cartilage defect that initially may be small still has the potential to have a physical and chemical "domino effect" on the surrounding "normal" articular cartilage. [2] Pitkin et al. (2014) discovered a potential etiology for articular cartilage damage. When the interarticular transmission of pressures is interrupted so that ...
Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible.
Autologous articular cartilage transfer from a non-weight-bearing area to the damaged area, called osteochondral autograft transfer system, is one possible procedure that is being studied. [140] When the missing cartilage is a focal defect, autologous chondrocyte implantation is also an option.