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Medications Certain medications, such as diuretics or steroids, can increase urination in our furry friends. If your dog has recently started a new medication, be aware of possible side effects.
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CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]
The actions of Δ 9-THC result from its partial agonist activity at the cannabinoid receptor CB 1 (K i = 40.7 nM [23]), located mainly in the central nervous system, and the CB 2 receptor (K i = 36 nM [23]), mainly expressed in cells of the immune system. [24] The psychoactive effects of THC are primarily mediated by the activation of (mostly G ...
CBD is a very low-affinity CB 1 ligand, that can nevertheless affect CB 1 receptor activity in vivo in an indirect manner, while THCV is a high-affinity CB 1 receptor ligand and potent antagonist in vitro and yet only occasionally produces effects in vivo resulting from CB 1 receptor antagonism.
Acute effects while under the influence can sometimes include euphoria or anxiety. [4] [5] Although some assert that cannabidiol (CBD), another cannabinoid found in cannabis in varying amounts, may alleviate the adverse effects of THC that some users experience, [6] little is known about CBD's effects on humans.
Most antidepressants aim for the same target: the monoamine system. They work by raising levels of one or more of the monoamine neurotransmitters in the brain that are involved in mood—serotonin ...
[1] [2] THC and CBD are stored mostly in the trichomes of the plant, [3] and can cause psychological and physical impairment in the user, via the endocannabinoid system and unique receptors. [4] [5] THC increases dopamine levels in the brain, which attributes to the euphoric and relaxed feelings cannabis provides.