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In the United States, asbestos is considered the major cause of malignant mesothelioma [27] and has been considered "indisputably" [28] associated with the development of mesothelioma. Indeed, the relationship between asbestos and mesothelioma is so strong that many consider mesothelioma a "signal" or "sentinel" tumor.
Asbestos (/ æ s ˈ b ɛ s t ə s, æ z-,-t ɒ s / ass-BES-təs, az-, -toss) [1] is a group of naturally occurring, toxic, carcinogenic and fibrous silicate minerals.There are six types, all of which are composed of long and thin fibrous crystals, each fibre (particulate with length substantially greater than width) [2] being composed of many microscopic "fibrils" that can be released into ...
Usually no symptoms shown but if exposure is extensive, it can cause lung impairment. Pneumothorax: Some reports have also linked the condition of pneumothorax to asbestos related diseases. Malignant mesothelioma: an aggressive and incurable tumour arising from mesothelial cells of the pleura (the lining of the thoracic cavity).
Some substances cause cancer primarily through their physical, rather than chemical, effects on cells. [32] A prominent example of this is prolonged exposure to asbestos, naturally occurring mineral fibers which are a major cause of mesothelioma, which is a cancer of the serous membrane, usually the serous membrane surrounding the lungs. [32]
Asbestos can cause lung cancer that is identical to lung cancer from other causes. Exposure to asbestos is associated with all major histological types of lung carcinoma (adenocarcinoma, squamous cell carcinoma, large-cell carcinoma and small-cell carcinoma). The latency period between exposure and development of lung cancer is 20 to 30 years.
This can result in shortness of breath, a common symptom exhibited by individuals with asbestosis. [24] Those with asbestosis may be more vulnerable to tumor growth (mesothelioma), because asbestos decreases the cytotoxicity of natural killer cells and impairs the functioning of T helper cells, which detect abnormal cell growth. [25]
Dusts that can cause cancer leather or wood dusts, asbestos, [2] crystalline forms of silica, coal tar pitch volatiles, coke oven emissions, diesel exhaust and environmental tobacco smoke. [1] sunlight; radon gas; and industrial, medical, or other exposure to ionizing radiation can all cause cancer in the workplace. Industrial processes ...
Interventions in areas where asbestos is present often have to follow stringent procedures. Asbestos is a known carcinogen. [5] It is the primary risk factor for mesothelioma, a cancer of the lining of the lungs. [6] It may cause other lung cancers and respiratory diseases such as asbestosis. [7]
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