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A genetic variant associated with ADHD has been found at higher frequency in more nomadic populations and those with more of a history of migration. [10] Consistent with this, the health status of nomadic Ariaal men was higher if they had the ADHD associated genetic variant (7R alleles), whereas in recently sedentary (non-nomadic) Ariaal ...
Large, high quality research has found small differences in the brain between ADHD and non-ADHD patients. [1] [15] Jonathan Leo and David Cohen, critics who reject the characterization of ADHD as a disorder, contended in 2003 and 2004 that the controls for stimulant medication usage were inadequate in some lobar volumetric studies, which makes it impossible to determine whether ADHD itself or ...
ADHD can be difficult to tell apart from other conditions. [16] [22] It represents the extreme lower end of the continuous dimensional trait (bell curve) of executive functioning and self-regulation, which is supported by twin, brain imaging and molecular genetic studies. [39] The precise causes of ADHD are unknown in most individual cases.
ADHD also has high rates of comorbidity with these disorders in adulthood, further leading clinicians to pursue evaluation for these disorders over ADHD. [10] Furthermore, the stigma surrounding ADHD causes many adults to forego seeking treatment altogether. [13] Another barrier to diagnosis is faced by highly intelligent or high-functioning ...
A 2017 study [8] [9] tested all 20,000 genes in about 4,300 families with children with rare developmental difficulties in the UK and Ireland in order to identify if these difficulties had a genetic cause. They found 14 new developmental disorders caused by spontaneous genetic mutations not found in either parent (such as a fault in the CDK13 ...
The estimate suggests that the condition is slightly less common than Rett syndrome, a genetic disorder that causes babies to rapidly lose coordination, speech and mobility and affects about 1 in ...
NF-1 is a complex multi-system human disorder caused by the mutation of a gene on chromosome 17 that is responsible for production of a protein, called neurofibromin 1, which is needed for normal function in many human cell types. NF-1 causes tumors along the nervous system which can grow anywhere on the body. NF-1 is one of the most common ...
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