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2,4-Dinitrophenylhydrazine (2,4-DNPH or DNPH) is the organic compound C 6 H 3 (NO 2) 2 NHNH 2. DNPH is a red to orange solid. It is a substituted hydrazine. The solid is relatively sensitive to shock and friction. For this reason DNPH is usually handled as a wet powder. DNPH is a precursor to the drug Sivifene.
Hydrazines (R 2 N−NR 2) are a class of chemical compounds with two nitrogen atoms linked via a covalent bond and which carry from one up to four alkyl or aryl substituents. Hydrazines can be considered as derivatives of the inorganic hydrazine (H 2 N−NH 2), in which one or more hydrogen atoms have been replaced by hydrocarbon groups. [1]
2,4-Dinitrophenol (2,4-DNP or simply DNP) is an organic compound with the formula HOC 6 H 3 (NO 2) 2. It has been used in explosives manufacturing and as a pesticide and herbicide. In humans, DNP causes dose-dependent mitochondrial uncoupling , causing the rapid loss of ATP as heat and leading to uncontrolled hyperthermia —up to 44 °C (111 ...
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Frederick Sanger. In 1945, Frederick Sanger described its use for determining the N-terminal amino acid in polypeptide chains, in particular insulin. [4] Sanger's initial results suggested that insulin was a smaller molecule than previously estimated (molecular weight 12,000), and that it consisted of four chains (two ending in glycine and two ending in phenylalanine), with the chains cross ...
R 2 C=N−NR' 2 + H 2 O → R 2 C=O + H 2 N−NR' 2. Alkyl hydrazones are 10 2 - to 10 3-fold more sensitive to hydrolysis than analogous oximes. [10] When derived from hydrazine itself, hydrazones condense with a second equivalent of a carbonyl to give azines: [11] R 2 C=N−NH 2 + R 2 C=O → R 2 C=N−N=CR 2 + H 2 O. Hydrazones are ...
2,4-DNP can mean: 2,4-Dinitrophenol, a small organic molecule formerly marketed as a pharmaceutical "diet aid" 2,4-Dinitrophenylhydrazine, Brady's reagent, used in ...
2,4-Dinitrochlorobenzene (DNCB) is an organic compound with the chemical formula (O 2 N) 2 C 6 H 3 Cl. It is a yellow solid that is soluble in organic solvents . It is an intermediate for the industrial production of other compounds.