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Most people recover within a week or so. In about 5% of cases, symptoms worsen and can become life-threatening. This is called severe dengue (formerly called dengue hemorrhagic fever or dengue shock syndrome). [21] [23] Severe dengue can lead to shock, internal bleeding, organ failure and even death. [24]
CLEC5A is responsible for dengue virus induced hemorrhagic fever and dengue shock syndrome (DSS), which is the most severe immune response to dengue virus infection and it is characterized by plasma leakage because of the increased vascular permeability. Interaction of CLEC5A and dengue virus also induces osteolytic activity. [8]
In a small proportion of cases, the disease develops into the life-threatening dengue hemorrhagic fever, resulting in bleeding, low levels of blood platelets and blood plasma leakage, or into dengue shock syndrome, where dangerously low blood pressure occurs. [2] Dengue is spread by several species of mosquito of the Aedes type, principally A ...
In a small proportion of cases the disease develops into the life-threatening dengue hemorrhagic fever, resulting in hemorrhage, thrombocytopenia and blood plasma leakage, or into dengue shock syndrome, where shock occurs. Dengue is transmitted by several species of mosquito within the genus Aedes, principally A. aegypti.
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In those outbreaks; dengue virus-2 was the infecting serotype. 205 cases of dengue hemorrhagic fever and dengue shock syndrome occurred during the 1997 outbreak, all in people older than 15 years. All but three of these cases were demonstrated to have been previously infected by dengue virus-1 during the first outbreak. [49]
Dengue virus (DENV) is the cause of dengue fever.It is a mosquito-borne, single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. [1] [2] Four serotypes of the virus have been found, and a reported fifth has yet to be confirmed, [3] [4] [5] all of which can cause the full spectrum of disease. [1]
29 May – 2013 dengue outbreak in Singapore: A man from Hougang dies from dengue shock syndrome; the first reported death case relating to dengue in Singapore this year. [ 46 ] 31 May – Peter Lim Sim Pang, a former Singapore Civil Defence Force commissioner, is found guilty in a sex-for-contracts scandal involving three women, subsequently ...