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18 November – Researchers report that CRISPR/Cas9, using a lipid nanoparticle delivery system, has been used to treat cancer effectively in a living animal for the first time. [ 90 ] [ 91 ] 25 November: The development of a biotechnology for microbial reactors capable of producing oxygen as well as hydrogen is reported.
CRISPR gene editing is a revolutionary technology that allows for precise, targeted modifications to the DNA of living organisms. Developed from a natural defense mechanism found in bacteria, CRISPR-Cas9 is the most commonly used system, that allows "cutting" of DNA at specific locations and either delete, modify, or insert genetic material.
1987: Yoshizumi Ishino discovers and describes part of a DNA sequence which later will be called CRISPR. 1989: Thomas Cech discovered that RNA can catalyze chemical reactions, [60] making for one of the most important breakthroughs in molecular genetics, because it elucidates the true function of poorly understood segments of DNA.
The CRISPR-Cas9 system consists of an enzyme called Cas9 and a special piece of guide RNA (gRNA). Cas9 acts as a pair of ‘molecular scissors’ that can cut the DNA at a specific location in the genome so that genes can be added or removed. The guide RNA has complementary bases to those at the target location, so it binds only there.
Herbert Boyer helped found the first genetic engineering company in 1976. In 1976 Genentech, the first genetic engineering company was founded by Herbert Boyer and Robert Swanson and a year later the company produced a human protein (somatostatin) in E.coli. Genentech announced the production of genetically engineered human insulin in 1978. [75]
[15] [16] The Moon's gravitational pull stabilised Earth's fluctuating axis of rotation, setting up regular climatic conditions favoring abiogenesis. [17] 4404 Ma Evidence of the first liquid water on Earth which were found in the oldest known zircon crystals. [18] 4280–3770 Ma Earliest possible appearance of life on Earth. [19] [20] [21] [22]
In December 2021, it was reported that the first CRISPR-gene-edited marine animal/seafood and second set of CRISPR-edited food has gone on public sale in Japan: two fish of which one species grows to twice the size of natural specimens due to disruption of leptin, which controls appetite, and the other grows to 1.2 the natural average size with ...
Human Nature is a 2019 documentary film directed by Adam Bolt and written by Adam Bolt and Regina Sobel. Producers of the film include Greg Boustead, Elliot Kirschner and Dan Rather . [ 1 ]