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Immunoreactive axonal profiles are observed as either granular (B, G, H) or more elongated, fusiform (F) swellings in the corpus callosum and the brain stem (H) at 24h post traumatic brain injury. Example of APP immunoreactive neurons (arrow heads) observed in the cortex underneath the impact site (E, G). No APP staining was observed in healthy ...
Lesions can be extra-axial, (occurring within the skull but outside of the brain) or intra-axial (occurring within the brain tissue). [24] Damage from TBI can be focal or diffuse, confined to specific areas or distributed in a more general manner, respectively; [25] however, it is common for both types of injury to exist in a given case. [25]
Symptoms of brain injuries can also be influenced by the location of the injury and as a result, impairments are specific to the part of the brain affected. Lesion size is correlated with severity, recovery, and comprehension. [16] Brain injuries often create impairment or disability that can vary greatly in severity. Studies show there is a ...
Hemorrhagic parenchymal contusions and cerebral microhemorrhages are examples of traumatic intra-axial bleeds. [3] Extra-axial hemorrhage, bleeding that occurs within the skull but outside of the brain tissue, falls into three subtypes: epidural hematoma, subdural hematoma, and subarachnoid hemorrhage. [3]
Symptoms of brain injuries can also be influenced by the location of the injury and as a result impairments are specific to the part of the brain affected. Lesion size is correlated with severity, recovery, and comprehension. [4] Brain injuries often create impairment or disability that can vary greatly in severity.
The symptoms depend on the cause of the blockage, the person's age, and how much brain tissue has been damaged by the swelling. [ 11 ] In infants with hydrocephalus, CSF builds up in the central nervous system (CNS), causing the fontanelle (soft spot) to bulge and the head to be larger than expected.
Symptoms of a brainstem stroke frequently include sudden vertigo and ataxia, with or without weakness. Brainstem stroke can also cause diplopia, slurred speech and decreased level of consciousness. A more serious outcome is locked-in syndrome. [citation needed]
Cerebral contusion (Latin: contusio cerebri), a form of traumatic brain injury, is a bruise of the brain tissue. [2] Like bruises in other tissues, cerebral contusion can be associated with multiple microhemorrhages, small blood vessel leaks into brain tissue. Contusion occurs in 20–30% of severe head injuries. [3]