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Cellulitis in 2015 resulted in about 16,900 deaths worldwide, up from 12,600 in 2005. [8] Cellulitis is a common global health burden, with more than 650,000 admissions per year in the United States alone. In the United States, an estimated 14.5 million cases annually of cellulitis account for $3.7 billion in ambulatory care costs alone.
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Cellulitis, a diffuse inflammation of connective tissue with severe inflammation of dermal and subcutaneous layers of the skin. [7] Further, cellulitis can be classified based into purulent and non-purulent cellulitis, based on the most likely causative agent and the symptoms presentation. [8]
Perianal cellulitis, also known as perianitis or perianal streptococcal dermatitis, is a bacterial infection affecting the lower layers of the skin around the anus. [1] [2] [3] It presents as bright redness in the skin and can be accompanied by pain, difficulty defecating, itching, and bleeding.
In contrast to cellulitis, erysipelas is a bacterial infection involving the more superficial layers of the skin, present with an area of redness with well-defined edges, and more often is associated with a fever.
Patients present with an acute onset of swelling, pain, erythema, prominent tenderness, warmness and limited range of motion in both ankles. [1] [2] Lower legs and heels may also be involved, however the distal parts of feet and toes are usually spared. Patients may also experience high-graded fever, pitting edema and hypotension.
Eosinophilic cellulitis, also known as Wells' syndrome (not to be confused with Weil's disease), is a skin disease that presents with painful, red, raised, and warm patches of skin. [2] The rash comes on suddenly, lasts for a few weeks, and often repeatedly comes back. [ 2 ]
Periorbital cellulitis, or preseptal cellulitis, is an inflammation and infection of the eyelid and portions of skin around the eye anterior to the orbital septum. [1] It may be caused by breaks in the skin around the eye, and subsequent spread to the eyelid; infection of the sinuses around the nose (); or from spread of an infection elsewhere through the blood.
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