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Critical closing pressure is the internal pressure at which a blood vessel collapses and closes completely. [1] When blood pressure falls below critical closing pressure, the vessel is unable to overcome external pressure (either from environment or vascular smooth muscle) and flow stops.
Blood pressure (BP) is the pressure of circulating blood against the walls of blood vessels. Most of this pressure results from the heart pumping blood through the circulatory system . When used without qualification, the term "blood pressure" refers to the pressure in a brachial artery , where it is most commonly measured.
The heart is supplied by coronary vessels, and therefore CPP is the blood pressure within those vessels. If pressures are too low in the coronary vasculature, then the myocardium risks ischemia (restricted blood flow) with subsequent myocardial infarction or cardiogenic shock .
Central aortic pressure (CAP), central aortic blood pressure (CABP), or central aortic systolic pressure (CASP) is the blood pressure at the root of aorta.Studies have shown the importance of central aortic pressure, especially as compared to peripheral blood pressure, and its implications in assessing the efficacy of antihypertensive treatment with respect to cardiovascular risk factors ...
An alternative definition of CPP is: [1] = where: MAP is mean arterial pressure ICP is intracranial pressure JVP is jugular venous pressure. This definition may be more appropriate if considering the circulatory system in the brain as a Starling resistor, where an external pressure (in this case, the intracranial pressure) causes decreased blood flow through the vessels.
Blood vessels do not actively engage in the transport of blood (they have no appreciable peristalsis). Blood is propelled through arteries and arterioles through pressure generated by the heartbeat. [18] Blood vessels also transport red blood cells. Hematocrit tests can be performed to calculate the proportion of red blood cells in the blood.
Note that, for cardiac function curve, "central venous pressure" is the independent variable and "systemic flow" is the dependent variable; for vascular function curve, the opposite is true. It shows a steep relationship at relatively low filling pressures and a plateau, where further stretch is not possible and so increases in pressure have ...
A plot of a system's pressure versus volume has long been used to measure the work done by the system and its efficiency. This analysis can be applied to heat engines and pumps, including the heart. A considerable amount of information on cardiac performance can be determined from the pressure vs. volume plot (pressure–volume diagram).