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Atomoxetine is sometimes used in the treatment of cognitive impairment and frontal lobe symptoms due to conditions like traumatic brain injury (TBI). [48] [49] It is used to treat ADHD-like symptoms such as sustained attentional problems, disinhibition, [50] lack of arousal, fatigue, and depression, including symptoms from cognitive disengagement syndrome. [48]
One recent study suggests that ADHD medication can help boost cognitive function. Another has found that people taking these drugs even have a lower risk of premature death. ... atomoxetine linked ...
Atomoxetine reaches C max 1 to 2 hours after administration. The bioavailability of atomoxetine after oral administration is 63-94%, it is dependent on individual differences in the first-pass metabolism. [18] Atomoxetine is widely distributed and is highly (98%) bound to plasma proteins, mainly albumin.
Based on the monoamine hypothesis of depression, which asserts that decreased concentrations of monoamine neurotransmitters leads to depressive symptoms, the following relations were determined: "Norepinephrine may be related to alertness and energy as well as anxiety, attention, and interest in life; [lack of] serotonin to anxiety, obsessions ...
Bright light therapy, a standard treatment for seasonal depression, may also help people who experience depression year-round, a study shows. Researchers found that patients with non-seasonal ...
The strong selective norepinephrine reuptake inhibitor (NRI), atomoxetine (Strattera), has been approved by the U.S. Food and Drug Administration (FDA) to treat ADHD in adults. [24] [25] The role of the NET in ADHD is similar to how it works to ease the symptoms of depression. The NET is blockaded by atomoxetine and increases NE levels in the ...
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