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But more recent data, including an analysis of 35,760 patients from 17 clinical trials, show that niacin has not been helpful in preventing any serious heart-related events like heart attack ...
High levels of niacin, an essential B vitamin, may raise the risk of heart disease by triggering inflammation and damaging blood vessels, according to new research.. The report, published Monday ...
Both studies were designed and conducted by the National Heart, Lung, and Blood Institute in the United States, each involving a large, randomized sample. [12] While the original study was designed to test the effects of several varying nutrients on blood pressure, DASH-Sodium varies only in salt content in the diet. [13]
N 1-Methyl-4-pyridone-3-carboxamide, also abbreviated as 4PY, is a breakdown product of niacin, [1] that is associated with an increased risk of cardiovascular disease. [2] It has 2 carbonyl groups that are close to each other.
A man with pellagra, which is caused by a chronic lack of vitamin B 3 in the diet. Severe deficiency of niacin in the diet causes the disease pellagra, characterized by diarrhea, sun-sensitive dermatitis involving hyperpigmentation and thickening of the skin (see image), inflammation of the mouth and tongue, delirium, dementia, and if left untreated, death. [7]
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Liver disease or kidney disease: Niacin can accumulate in people with liver or kidney problems, potentially worsening their condition. [1] Bleeding disorders: Inositol nicotinate may slow blood clotting, increasing the risk of bleeding for individuals with clotting disorders or those undergoing surgery. [1]
Worth noting: Bob Harper wrote a book touting this diet after he suffered a heart attack. Anti-Inflammatory Diet The basics: Low sugar, emphasis on fish over meat, healthy oils and fats.