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There is little modern clinical research on Dioscorea villosa, and the one study of a wild yam-containing cream for menopausal symptoms failed to find any value from this therapy. [18] According to the American Cancer Society, there is no evidence to support wild yam or diosgenin being either safe or effective in humans. [19]
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"The primary treatment — and the first-line treatment — should be hormone (estrogen) therapy, especially for moderate-to-severe menopause symptoms," Dr. Anna Barbieri, assistant clinical ...
Diosgenin, a phytosteroid sapogenin, is the product of hydrolysis by acids, strong bases, or enzymes of saponins, extracted from the tubers of Dioscorea wild yam species, such as the Kokoro. It is also present in smaller amounts in a number of other species.
Dioscorea bulbifera (commonly known as the air potato, air yam, bitter yam, cheeky yam, potato yam, [2] aerial yam, [3] and parsnip yam [4]) is a species of true yam in the yam family, Dioscoreaceae. It is native to Africa, Asia and northern Australia. [ 1 ]
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