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2. Talimogene laherparepvec - Wikipedia

   en.wikipedia.org/wiki/Talimogene_laherparepvec

   Talimogene laherparepvec is a genetically engineered herpes virus (an oncolytic herpes virus). Two genes were removed – one that shuts down an individual cell's defenses, and another that helps the virus evade the immune system – and a gene for human GM-CSF was added. The drug works by replicating in cancer cells, causing them to burst; it ...

3. Tzanck test - Wikipedia

   en.wikipedia.org/wiki/Tzanck_test

   The most common reason to use cytological examination in malignant tumoral diseases is to distinguish basal cell carcinoma from other tumors, such as squamous cell carcinoma and melanoma. Tzanck smear test is 97% sensitivity and 86% specificity for the diagnosis of basal cell carcinoma. Squamous cell carcinoma: Cytologic atypia of keratinocytes

4. Oncolytic virus - Wikipedia

   en.wikipedia.org/wiki/Oncolytic_virus

   The herpes simplex virus type 1 (HSV-1) mutant 1716 lacks both copies of the ICP34.5 gene, and as a result is no longer able to replicate in terminally differentiated and non-dividing cells but will infect and cause lysis very efficiently in cancer cells, and this has proved to be an effective tumour-targeting strategy.

5. Cutaneous squamous-cell carcinoma - Wikipedia

   en.wikipedia.org/wiki/Cutaneous_squamous-cell...

   Cutaneous squamous-cell carcinoma (cSCC), also known as squamous-cell carcinoma of the skin or squamous-cell skin cancer, is one of the three principal types of skin cancer, alongside basal-cell carcinoma and melanoma. [10] cSCC typically presents as a hard lump with a scaly surface, though it may also present as an ulcer. [1]

6. Oncolytic herpes virus - Wikipedia

   en.wikipedia.org/wiki/Oncolytic_herpes_virus

   Squamous cell carcinoma of head and neck: A phase I trial has been completed. [8] Malignant melanoma: A phase I trial has been completed. [9] Hepatocellular carcinoma: A phase I/II trial is in preparation. Malignant pleural mesothelioma: A phase I/II trial is in progress. [10] Non-CNS pediatric cancer: A phase I trial is in progress. [11]

7. Wart - Wikipedia

   en.wikipedia.org/wiki/Wart

   Callus, seborrheic keratosis, squamous cell carcinoma [4] Prevention: Avoiding skin contact with infected individual, not walking barefoot in public areas, having safe sex or sexual abstinence: Treatment: Salicylic acid, cryotherapy, [1] surgical removal: Frequency: Very common [2]

8. Herpesviridae - Wikipedia

   en.wikipedia.org/wiki/Herpesviridae

   Nine herpesvirus types are known to primarily infect humans, [7] at least five of which are extremely widespread among most human populations, and which cause common diseases: herpes simplex 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial and genital herpes), varicella zoster (VZV or HHV-3; the cause ...

9. Skin cancer - Wikipedia

   en.wikipedia.org/wiki/Skin_cancer

   Dermatoscopy may be useful in diagnosing basal cell carcinoma in addition to skin inspection. [42] There is insufficient evidence that optical coherence tomography (OCT) is useful in diagnosing melanoma or squamous cell carcinoma. OCT may have a role in diagnosing basal cell carcinoma but more data is needed to support this. [43]