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The terminal web is a filamentous structure found at the apical surface of epithelial cells that possess microvilli. It is composed primarily of actin filaments stabilized by spectrin, which also anchors the terminal web to the apical cell membrane. The presence of myosin II and tropomyosin helps to explain the contractile ability of the ...
The plus ends of the actin filaments are located at the tip of the microvillus and are capped, possibly by capZ proteins, [2] while the minus ends are anchored in the terminal web composed of a complicated set of proteins including spectrin and myosin II. The space between microvilli at a cell's surface is called the intermicrovillous space.
Other cellular extensions that protrude from the cell membrane are known as membrane protrusions or cell protrusions, also cell appendages, such as flagella, and microvilli. [8] [9] Microtentacles are cell protrusions attached to free-floating cells, associated with the spread of some cancer cells. [10]
Between the ciliated cells are numerous microvilli, attached as tufts to brush cells sometimes referred to as pulmonary brush cells; [9] these are also known as the tuft cells of the gastrointestinal tract, or intestinal tuft cells, [10] although there is a difference between the two types: the brush cells lack the terminal web that lies under ...
Villin-1 is made up of seven domains, six homologous domains make up the N-terminal core and the remaining domain makes up the C-terminal cap. [3] Villin contains three phosphatidylinositol 4,5-biphosphate (PIP 2) binding sites, one of which is located at the head piece and the other two in the core. [5]
The chemotherapy drug 5-FU can be toxic to some people with cancer. A quick, cheap test can show if chemo is safe for a patient, but few doctors order it.
Club cells, also known as bronchiolar exocrine cells, [1] are low columnar/cuboidal cells with short microvilli, found in the small airways (bronchioles) of the lungs. [2] They were formerly known as Clara cells. Club cells are found in the ciliated simple epithelium. These cells may secrete glycosaminoglycans to protect the bronchiole lining.
Bull Run Festival of Lights in Centreville, VA. Get ready to light up your holidays with this 2.5-mile drive-through extravaganza! Take a ride bursting with festive scenes, glowing characters, and ...
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