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  2. Keratinocyte - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte

    In humans, they constitute 90% of epidermal skin cells. [1] Basal cells in the basal layer (stratum basale) of the skin are sometimes referred to as basal keratinocytes. [2] Keratinocytes form a barrier against environmental damage by heat, UV radiation, water loss, pathogenic bacteria, fungi, parasites, and viruses.

  3. Human skin - Wikipedia

    en.wikipedia.org/wiki/Human_skin

    The human skin is the outer covering of the body and is the largest organ of the ... Epidermal Keratinocytes 1.1E+11 85.5 10.1% Hair Follicle 1.3E+11 119.9 ...

  4. List of human cell types derived from the germ layers

    en.wikipedia.org/wiki/List_of_human_cell_types...

    This is a list of cells in humans derived from the three embryonic germ layers – ectoderm, mesoderm, and endoderm. Cells derived from ectoderm. Surface ectoderm

  5. Epidermis - Wikipedia

    en.wikipedia.org/wiki/Epidermis

    The epidermis is the outermost of the three layers that comprise the skin, the inner layers being the dermis and hypodermis. [1] The epidermal layer provides a barrier to infection from environmental pathogens [2] and regulates the amount of water released from the body into the atmosphere through transepidermal water loss.

  6. Skin sloughing - Wikipedia

    en.wikipedia.org/wiki/Skin_sloughing

    The programmed cell death prevents the activity of damaged DNA or pathways that could otherwise lead to cancer. In the process, however, keratinocytes are killed. If the keratinocytes that apoptose are in the lowest layer of the skin, this can be an issue. Typically, however, keratinocytes in higher layers are able to slough away normally.

  7. Stratum spinosum - Wikipedia

    en.wikipedia.org/wiki/Stratum_spinosum

    This layer is composed of polyhedral keratinocytes. [3] [4] These are joined with desmosomes. [3] Their spiny (Latin, spinosum) appearance is due to shrinking of the microfilaments between desmosomes that occurs when stained with H&E. Keratinization begins in the stratum spinosum, [5] although the actual keratinocytes begin in the stratum ...

  8. Keratinocyte transglutaminase - Wikipedia

    en.wikipedia.org/wiki/Keratinocyte_transglutaminase

    A deficiency is associated with ichthyosis lamellaris. [11] Epidermal transglutaminase is the autoantigen, in humans, of dermatitis herpetiformis.. A study on the mutation of keratinocyte transglutaminase (TGK) came to conclude that those affected with ichthyosis lamellaris, present a substantial deficit in keratinocyte transglutaminase activity. [8]

  9. HaCaT - Wikipedia

    en.wikipedia.org/wiki/HaCaT

    HaCaT is a spontaneously transformed aneuploid immortal keratinocyte cell line from adult human skin, [1] [2] widely used in scientific research. [3] HaCaT cells are utilized for their high capacity to differentiate and proliferate in vitro. [4]

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