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A hilar cell tumor is an androgen-producing ovarian tumor that is most commonly found in older women and often leads to the development of male sex characteristics. The tumor tends to occur around the region of the ovary where the blood vessels enter the organ, known as the hilum. This type of tumor tends to be small in size and in most cases ...
Sertoli–Leydig cell tumour is a testosterone-secreting ovarian tumor and is a member of the sex cord-stromal tumour group [2] of ovarian and testicular cancers. The tumour occurs in early adulthood (not seen in newborn), is rare, comprising less than 1% of testicular tumours. [ 1 ]
The majority of Leydig cell tumors are found in males, usually at 5–10 years of age or in middle adulthood (30–60 years). Children typically present with precocious puberty. [citation needed] Due to excess testosterone secreted by the tumour, one-third of female patients present with a recent history of progressive masculinization.
PCOS is a common reason why women have difficulty getting pregnant. ... polycystic ovaries and elevated androgen levels, ... Cushing's syndrome or androgen-secreting tumors — that may mimic PCOS
Androgen-secreting tumors: These are rare tumors that produce androgens and can cause acne in both men and women (though the tumors are more common in women). Deposit Photos. Genetics.
Polycystic ovary syndrome, or polycystic ovarian syndrome (PCOS), is the most common endocrine disorder in women of reproductive age. [14] The syndrome is named after cysts which form on the ovaries of some women with this condition, though this is not a universal symptom and not the underlying cause of the disorder.
An androgen-dependent condition, disease, disorder, or syndrome, is a medical condition that is, in part or full, dependent on, or is sensitive to, the presence of androgenic activity in the body. [ citation needed ]
Leydig cells release a class of hormones called androgens (19-carbon steroids). [8] They secrete testosterone, androstenedione and dehydroepiandrosterone (DHEA), when stimulated by the luteinizing hormone (LH), which is released from the anterior pituitary in response to gonadotropin releasing hormone which in turn is released by the hypothalamus.