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Subclinical hypothyroidism is a biochemical diagnosis characterized by an elevated serum TSH level, but with a normal serum free thyroxine level. [47] [48] [49] The incidence of subclinical hypothyroidism is estimated to be 3-15% and a higher incidence is seen in elderly people, females and those with lower iodine levels. [47]
People with high TSH and low T4 get a diagnosis of hypothyroidism. Those with slightly elevated TSH and slightly low T4 get a diagnosis of subclinical hypothyroidism, which might be treated with ...
Abnormal thyroid function tests without any clinical symptoms (subclinical hypothyroidism or subclinical hyperthyroidism). [ 2 ] In the US, hypothyroidism and hyperthyroidism were respectively found in 4.6 and 1.3% of the >12y old population (2002).
Overt, symptomatic thyroid dysfunction is the most common complication, with about 5% of people with subclinical hypothyroidism and chronic autoimmune thyroiditis progressing to thyroid failure every year.
Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively. [8] Endemic iodine deficiency accounts for most hypothyroidism in pregnant women worldwide while chronic autoimmune thyroiditis is the most common cause of hypothyroidism in iodine sufficient parts of the world.
Subclinical hypothyroidism (35% of cases) Overt hypothyroidism (20% of cases) ... The patient was a 48-year-old man with hypothyroidism, multiple episodes of ...
Levothyroxine is also used to treat subclinical hypothyroidism, which is defined by an elevated TSH level and a normal-range free T 4 level without symptoms. [14] Such people may be asymptomatic [14] and whether they should be treated is controversial. [13]
It is unclear if this finding reflects shortcomings of the index (i.e. low specificity in the setting of subclinical hypothyroidism) or plastic responses of the pituitary gland to beginning hypothyroidism. [citation needed] In subjects with type 2 diabetes, treatment with beta blockers resulted in increased TSH index, but the mechanism is ...
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