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  2. Serotonin–norepinephrine–dopamine reuptake inhibitor

    en.wikipedia.org/wiki/Serotonin–norepinephrine...

    In discussing cocaine and related compounds such as amphetamines, it is clear that these psychostimulants cause increased blood pressure, decreased appetite (and hence weight loss), increased locomotor activity (LMA) etc. In the United States, cocaine overdose is one of the leading causes of ER admissions each year due to drug overdose. [182]

  3. Cocaine - Wikipedia

    en.wikipedia.org/wiki/Cocaine

    Additionally, stimulants like cocaine, methamphetamine, and even caffeine cause dehydration and dry mouth. Since saliva is an important mechanism in maintaining one's oral pH level, people who use cocaine over a long period of time who do not hydrate sufficiently may experience demineralization of their teeth due to the pH of the tooth surface ...

  4. Cocaine dependence - Wikipedia

    en.wikipedia.org/wiki/Cocaine_dependence

    Cocaine is a powerful stimulant known to make users feel energetic, cheerful, talkative, etc. In time, negative side effects include increased body temperature, irregular or rapid heart rate, high blood pressure, increased risk of heart attacks, strokes and even sudden death from cardiac arrest.

  5. What's driving the permanent crisis of drug addiction? - AOL

    www.aol.com/whats-driving-permanent-crisis-drug...

    The crack cocaine epidemic arrived in the next decade, followed by a rise in the use of methamphetamines, which the late Senator Dianne Feinstein would call the "drug epidemic of the nineties."

  6. Recreational drug use - Wikipedia

    en.wikipedia.org/wiki/Recreational_drug_use

    Depressants are psychoactive drugs that temporarily diminish the function or ... (reduction of anxiety), analgesia (pain relief ... Cocaine is a commonly used stimulant.

  7. What Exactly Is Pink Cocaine? An Expert Explains the ... - AOL

    www.aol.com/exactly-pink-cocaine-expert-explains...

    The headline-making drug "pink cocaine" has been mentioned in the ongoing Sean "Diddy" Combs sex trafficking case and was linked to the death of One Direction star Liam Payne

  8. Depressant - Wikipedia

    en.wikipedia.org/wiki/Depressant

    Some specific depressants do influence mood, either positively (e.g., opioids) or negatively, but depressants often have no clear impact on mood (e.g., most anticonvulsants). In contrast, stimulants, or "uppers", increase mental alertness, making stimulants the opposite drug class from depressants.

  9. As overdose rates rise, FDA calls for new medications to help ...

    www.aol.com/news/why-no-treatments-cocaine-meth...

    Stimulants, such as cocaine and meth, elevate levels of a chemical in the brain called dopamine, which is responsible for regulating mood and producing feelings of pleasure and euphoria.