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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]
Severe serotonin syndrome can be life-threatening. Signs include: ... If you experience any signs or symptoms that might indicate you have serotonin syndrome, you need to seek medical treatment ...
Treatment is dependent on the severity of the discontinuation reaction and whether or not further antidepressant treatment is warranted. In cases where further antidepressant treatment is prescribed, then the only option suggested may be restarting the antidepressant. If antidepressants are no longer required, treatment depends on symptom severity.
The most commonly reported severe effect following SSRI overdose is serotonin syndrome; serotonin toxicity is usually associated with very high overdoses or multiple drug ingestion. [173] Other reported significant effects include coma, seizures, and cardiac toxicity. [170]
There may also be imbalances in mood-regulating neurotransmitters (brain chemicals) like dopamine and serotonin. But this isn’t well understood, either. But this isn’t well understood, either.
Overdose is usually treated symptomatically, especially in the case of serotonin syndrome, which requires treatment with cyproheptadine and temperature control based on the progression of the serotonin toxicity. [86] Patients are often monitored for vitals and airways cleared to ensure that they are receiving adequate levels of oxygen.
Follow-up treatment is still poorly studied, but about half of people who respond relapse with twelve months. [144] Aside from effects in the brain, the general physical risks of ECT are similar to those of brief general anesthesia. [145]: 259 Immediately following treatment, the most common adverse effects are confusion and memory loss.
“GLP-1 medications impact all of the neurotransmitters in the brain associated with mental health—norepinephrine, serotonin, and dopamine,” says Sue Decotiis, MD, a weight loss doctor based ...