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Ageing (or aging in American English) is the process of becoming older.The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. [1]
The misfolding of proteins is a common component of the proposed pathophysiology of many aging-related diseases. However, there is insufficient evidence to prove this. For example, the tau hypothesis for Alzheimer's proposes that tau protein accumulation results in the breakdown of neuron cytoskeletons, leading to Alzheimer's. [25]
Such an ageing process may include qualitative and quantitative changes and includes diminished or defective synthesis of collagen and elastin in the dermis. [citation needed] Extrinsic ageing of skin is a distinctive declination process caused by external factors, which include ultra-violet radiation, cigarette smoking, air pollution, among ...
Aging is natural. Some people age faster than others, often due to lifestyle factors. Here are signs your body may be aging early and how to prevent these changes.
Normal aging is associated with telomere shortening in both humans and mice, and studies on genetically modified animal models suggest causal links between telomere erosion and aging. [10] Leonard Hayflick demonstrated that a normal human fetal cell population will divide between 40 and 60 times in cell culture before entering a senescence phase.
Age-related memory loss is believed to originate in the dentate gyrus, whereas Alzheimer's is believed to originate in the entorhinal cortex. [33] During normal aging, oxidative DNA damage in the brain accumulates in the promoters of genes involved in learning and memory, as well as in genes involved in neuronal survival. [34]
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A HOME ISN'T ALWAYS THE HOUSE WE LIVE IN. IT'S ALSO THE PEOPLE WE CHOOSE TO SURROUND OURSELVES WITH. - T.J. KLUNE (Distributed by King Features) Cryptoquip.