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Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...
Central nervous system fatigue, or central fatigue, is a form of fatigue that is associated with changes in the synaptic concentration of neurotransmitters within the central nervous system (CNS; including the brain and spinal cord) which affects exercise performance and muscle function and cannot be explained by peripheral factors that affect muscle function.
The largest contribution to the allostatic load is the effect of stress on the brain. Allostasis is the system which helps to achieve homeostasis. [18] Homeostasis is the regulation of physiological processes, whereby systems in the body respond to the state of the body and to the external environment. [18]
According to the classes of organisms, the field can be divided into medical physiology, animal physiology, plant physiology, cell physiology, and comparative physiology. [4] Central to physiological functioning are biophysical and biochemical processes, homeostatic control mechanisms, and communication between cells. [5]
Short-term synaptic depression can affect many synapses of many different types of neurons. [5] The existence and observations of synaptic fatigue are accepted universally, although the exact mechanisms underlying the phenomenon are not completely understood. It is generally seen in mature cells at high frequencies of stimuli (>1 Hz).
Body memory (BM) is a hypothesis that the body itself is capable of storing memories, as opposed to only the brain. While experiments have demonstrated the possibility of cellular memory [1] there are currently no known means by which tissues other than the brain would be capable of storing memories.
In support of this, placebos (which must be mediated by a central process) have a powerful effect upon not only fatigue in prolonged exercise, [12] [13] but also upon short term endurance exercise such as sprint speed, [14] the maximum weight that could be lifted with leg extension, [15] and the tolerance of ischemic pain and power when a ...
Cell physiology is the biological study of the activities that take place in a cell to keep it alive. The term physiology refers to normal functions in a living organism . [ 1 ] Animal cells , plant cells and microorganism cells show similarities in their functions even though they vary in structure.