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One of their recent publications was a 2019 meta-analysis of menopausal hormone therapy and breast cancer risk based on type and timing of therapy. [1] In 2012, the group concluded in a meta-analysis of 117 studies that the incidence of breast cancer was increased by each year younger at menarche and each year older at menopause. [4]
There is a non-statistically significant increased rate of breast cancer for hormone replacement therapy with synthetic progestogens. [6] The risk may be reduced with bioidentical progesterone, [63] though the only prospective study that suggested this was underpowered due to the rarity of breast cancer in the control population.
IUD use linked to 14 breast cancer cases per every 10,000 women Study participants were followed from the year they started until December 2022, equaling an average of 6.8 years.
Hormone therapy is typically not recommended for anyone with a personal medical history of breast or uterine cancer, undiagnosed postmenopausal bleeding, active liver disease, heart attack, stroke ...
That’s also true of hormone replacement therapy (HRT) — the longer you’re on it, the higher the risk of breast cancer. Try to find nonhormonal methods of effective contraception, like an IUD ...
Moreover, breast cancer risk is heightened following use of the combined oral contraceptive pill and combined hormone replacement therapy. [4] Armed with this evidence that endogenous and exogenous changes in estrogen and progesterone levels modulate the risk of breast cancer, it is apparent that hormones can play a key role in breast cancer.
Hormone replacement therapy for treatment of menopause symptoms can also increase a woman's risk of developing breast cancer, though the effect depends on the type and duration of therapy. [ 90 ] [ 91 ] Combined progesterone /estrogen therapy increases breast cancer risk – approximately doubling one's risk after 6–7 years of treatment ...
Hormone-modulating therapy for breast cancer is associated with a 7% lower risk of developing Alzheimer's disease and related dementias later in life, a new study indicates.
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