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Hypoxemia is usually defined in terms of reduced partial pressure of oxygen (mm Hg) in arterial blood, but also in terms of reduced content of oxygen (ml oxygen per dl blood) or percentage saturation of hemoglobin (the oxygen-binding protein within red blood cells) with oxygen, which is either found singly or in combination. [2] [5]
Continued low oxygen levels may lead to respiratory or cardiac arrest. Oxygen therapy may be used to assist in raising blood oxygen levels. Oxygenation occurs when oxygen molecules (O 2) enter the tissues of the body. For example, blood is oxygenated in the lungs, where oxygen molecules travel from the air and into the blood. Oxygenation is ...
Hypoxia can be due to external causes, when the breathing gas is hypoxic, or internal causes, such as reduced effectiveness of gas transfer in the lungs, reduced capacity of the blood to carry oxygen, compromised general or local perfusion, or inability of the affected tissues to extract oxygen from, or metabolically process, an adequate supply ...
In medicine, oxygen saturation refers to oxygenation, or when oxygen molecules (O 2) enter the tissues of the body. In this case blood is oxygenated in the lungs, where oxygen molecules travel from the air into the blood. Oxygen saturation ((O 2) sats) measures the percentage of hemoglobin binding sites in the bloodstream occupied by oxygen ...
Gas exchange occurs in the lungs, whereby CO 2 is released from the blood, and oxygen is absorbed. The pulmonary vein returns the now oxygen-rich blood to the left atrium. [10] A separate circuit from the systemic circulation, the bronchial circulation supplies blood to the tissue of the larger airways of the lung.
The decreased binding to carbon dioxide in the blood due to increased oxygen levels is known as the Haldane effect, and is important in the transport of carbon dioxide from the tissues to the lungs. A rise in the partial pressure of CO 2 or a lower pH will cause offloading of oxygen from hemoglobin, which is known as the Bohr effect.
Hemoglobin has an oxygen-binding capacity of 1.34 mL of O 2 per gram, [6] which increases the total blood oxygen capacity seventy-fold compared to dissolved oxygen in blood plasma alone. [7] The mammalian hemoglobin molecule can bind and transport up to four oxygen molecules. [8] Hemoglobin also transports other gases.
Arterial blood is the oxygenated blood in the circulatory system found in the pulmonary vein, the left chambers of the heart, and in the arteries. [1] It is bright red in color, while venous blood is dark red in color (but looks purple through the translucent skin). It is the contralateral term to venous blood. [citation needed]