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  2. 5α-Reductase inhibitor - Wikipedia

    en.wikipedia.org/wiki/5α-reductase_inhibitor

    5-ARIs are clinically used in the treatment of conditions that are exacerbated by DHT: [3] Mild-to-moderate benign prostatic hyperplasia and lower urinary tract symptoms; Pattern hair loss in both men and women; 5-ARIs can be used in the treatment of hirsutism in women. [1] The usefulness of 5-ARIs for the potential treatment of acne is uncertain.

  3. List of 5α-reductase inhibitors - Wikipedia

    en.wikipedia.org/wiki/List_of_5α-reductase...

    This is a list of 5α-reductase inhibitors (5α-RIs), drugs which inhibit one or more isoforms of the enzyme 5α-reductase.This enzyme is responsible for the conversion of the androgen hormone testosterone into the more potent dihydrotestosterone (DHT) and is essential for the production of neurosteroids like allopregnanolone, tetrahydrodeoxycorticosterone (THDOC), and 3α-androstanediol from ...

  4. The 10 Best Saw Palmetto Shampoos in 2024 - AOL

    www.aol.com/entertainment/10-best-saw-palmetto...

    Saw palmetto inhibits the production of DHT by blocking the enzyme 5-alpha-reductase, which converts testosterone into DHT. By reducing the production of DHT, saw palmetto can help prevent hair loss.

  5. How Effective Is Saw Palmetto as a Hair Loss Treatment? - AOL

    www.aol.com/lifestyle/effective-saw-palmetto...

    Considering 30 to 50 percent of men are affected by hair loss by age 50 — it’s no surprise that some turn to herbal remedies like saw palmetto.

  6. Management of hair loss - Wikipedia

    en.wikipedia.org/wiki/Management_of_hair_loss

    Hair follicle with mesenchymal dermal papilla, labelled at top, location of hair follicle stem cells and thought to be site of action of DHT. Type 1 and 2 5α reductase enzymes are present at pilosebaceous units in papillae of individual hair follicles. They catalyse formation of the androgens testosterone and DHT, which in turn regulate hair ...

  7. This Chronic Skin Condition Is A Common Cause Of Dark ... - AOL

    www.aol.com/lifestyle/chronic-skin-condition...

    In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...

  8. Dutasteride - Wikipedia

    en.wikipedia.org/wiki/Dutasteride

    Dutasteride is approved for the treatment of male androgenetic alopecia in South Korea and Japan at a dosage of 0.5 mg per day. [6] [17] Several studies have found it to induce hair regrowth in men more rapidly and to a greater extent than even the highest approved dosage of finasteride.

  9. 5α-Reductase - Wikipedia

    en.wikipedia.org/wiki/5α-Reductase

    After birth, the 5α-R1 is expressed in more locations, including the liver, skin, scalp and prostate. 5α-R2 is expressed in prostate, seminal vesicles, epididymis, liver, and to a lesser extent the scalp and skin. Hepatic expression of both 5α-R1 and 2 is immediate, but disappears in the skin and scalp at month 18. Then, at puberty, only 5α ...

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