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Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth, often in the form of hydroxychloroquine sulfate. [3]
Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [64] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [65] Neither drug has been useful to prevent or treat SARS-CoV-2 infection.
One such cocktail – hydroxychloroquine combined with a high dose of zinc (as a sulfate, 220 mg (50 mg elemental Zn) per day for five days, a zinc dose ~4 times higher than the reference daily intake level) [63] and an approved antibiotic, either azithromycin or doxycycline – began in May as a Phase IV trial in New York State. [65]
Chloroquine retinopathy is a form of toxic retinopathy (damage of the retina) caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. [3]
Adult-onset Still's disease (AOSD) is a form of Still's disease, a rare systemic autoinflammatory disease characterized by the classic triad of fevers, joint pain, and a distinctive salmon-colored bumpy rash. The disease is considered a diagnosis of exclusion. [1] Levels of the iron-binding protein ferritin may be extremely elevated with this ...
Baricitinib (an immunomodulatory drug used in rheumatoid arthritis) Dimethyl fumarate (adults only, early phase assessment) Infliximab (adults only) High-dose dexamethasone (adults with hypoxia only) Children with PIMS-TS may also be allocated the following: [10] Low-dose dexamethasone (a steroid, which reduces inflammation) Intravenous ...
Both hydroxychloroquine and chloroquine have a side effect of retinal toxicity when administered to infected patients. [13] Adverse effects of the drug chloroquine include agitation, anxiety, confusion, gastrointestinal discomfort, [13] blurring vision and/or irreversible retinopathy. Sulfadoxine-pyrimethamine (SP) is administered to pregnant ...
Atovaquone/proguanil, sold under the brand name Malarone among others, is a fixed-dose combination medication used to treat and prevent malaria, including chloroquine-resistant malaria. [2] [3] It contains atovaquone and proguanil. [3] It is not recommended for severe or complicated malaria. [3] It is taken by mouth. [3]
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109 S High St #100, Columbus, OH · Directions · (614) 224-4261