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The blood tests QuantiFERON-TB Gold In-Tube and T-SPOT.TB use these antigens to detect people with tuberculosis. Lymphocytes from the patient's blood are incubated with the antigens. These tests are called interferon γ tests and are not equivalent. [19] If the patient has been exposed to tuberculosis before, T lymphocytes produce interferon γ ...
In December 2010, the World Health Organization (WHO) endorsed the Xpert MTB/RIF for use in tuberculosis (TB) endemic countries. [3] The announcement followed 18 months of assessing its field effectiveness in tuberculosis, MDR-TB, and TB/HIV co-infection. [4] The test may enable the diagnosis of TB in patients likely to be missed by traditional ...
T-SPOT.TB counts the number of antimycobacterial effector T cells, white blood cells that produce interferon-gamma, in a sample of blood.This gives an overall measurement of the host immune response against mycobacteria, which can reveal the presence of infection with Mycobacterium tuberculosis, the causative agent of tuberculosis (TB).
TB kills more than one million people each year, according to the World Health Organisation. Blood test could identify millions of people spreading tuberculosis unknowingly Skip to main content
Persons with recent contacts with a TB patient; Persons with nodular or fibrotic changes on chest X-ray consistent with old healed TB; Patients with organ transplants, and other immunosuppressed patients; 10 mm or more is positive in Recent arrivals (less than five years) from high-prevalence countries; Injection drug users
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The latter test determines the total number of individual effector T cells expressing IFN-γ. [citation needed] The indications for the test are still disputed. It has been evaluated for the diagnosis of latent tuberculosis in HIV patients (who frequently have a negative Mantoux test). [4]
Nine tuberculosis patients have been hospitalized and one has died, according to the health department. As of Monday, about 175 people had been exposed to tuberculosis as a result of the outbreak.
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