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  2. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin may be useful in the treatment of delayed sleep phase syndrome. [9] Melatonin is known to reduce jet lag, especially in eastward travel. However, if it is not taken at the correct time, it can instead delay adaptation. [30] Melatonin appears to have limited use against the sleep problems of people who work shift work. [31]

  3. You Shouldn’t Give Babies Melatonin, But Here’s ... - AOL

    www.aol.com/news/shouldn-t-babies-melatonin...

    Children can be notoriously bad sleepers, so who could blame a parent or caregiver for considering melatonin? Here’s what experts want you to know before giving it to kids, including safety ...

  4. Melatonin - Wikipedia

    en.wikipedia.org/wiki/Melatonin

    Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.

  5. 6-Hydroxymelatonin - Wikipedia

    en.wikipedia.org/wiki/6-Hydroxymelatonin

    6-Hydroxymelatonin (6-OHM) is a naturally occurring, endogenous, major active metabolite of melatonin. [1] 6-Hydroxymelatonin is produced as a result of the enzymatic conversion of melatonin through hydroxylation. [2] Similar to melatonin, 6-OHM is a full agonist of the MT 1 and MT 2 receptors.

  6. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [3] The half-life and duration of ramelteon are much longer than those of melatonin. [7] Ramelteon is not a benzodiazepine or Z-drug and does not interact with GABA receptors, instead having a distinct mechanism of action. [3] [8]

  7. N-Acetylserotonin - Wikipedia

    en.wikipedia.org/wiki/N-Acetylserotonin

    N-Acetylserotonin (NAS), also known as normelatonin, is a naturally occurring chemical intermediate in the endogenous production of melatonin from serotonin. [1] [2] It also has biological activity in its own right, including acting as a melatonin receptor agonist, an agonist of the TrkB, and having antioxidant effects.

  8. Nitrazepam - Wikipedia

    en.wikipedia.org/wiki/Nitrazepam

    Nitrazepam at doses of 5 mg or higher impairs driving skills [33] and like other hypnotic drugs, it is associated with an increased risk of traffic accidents. [34] In the elderly, nitrazepam is associated with an increased risk of falls and hip fractures due to impairments of body balance. [ 35 ]

  9. Light effects on circadian rhythm - Wikipedia

    en.wikipedia.org/wiki/Light_effects_on_circadian...

    [11] [12] [8] An advance means that the individual will tend to wake up earlier on the following day(s). A delay, caused by light exposure before sleeping, means that the individual will tend to wake up later on the following day(s). The hormones cortisol and melatonin are affected by the signals light sends through the body's nervous system ...

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