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20665 Ensembl ENSG00000100146 ENSMUSG00000033006 UniProt P56693 Q04888 RefSeq (mRNA) NM_006941 NM_011437 RefSeq (protein) NP_008872 NP_035567 Location (UCSC) Chr 22: 37.97 – 37.99 Mb Chr 15: 79.04 – 79.05 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor SOX-10 is a protein that in humans is encoded by the SOX10 gene. Function This gene encodes a member of the ...
A nerve guidance conduit (also referred to as an artificial nerve conduit or artificial nerve graft, as opposed to an autograft) is an artificial means of guiding axonal regrowth to facilitate nerve regeneration and is one of several clinical treatments for nerve injuries.
Axon guidance (also called axon pathfinding) is a subfield of neural development concerning the process by which neurons send out axons to reach their correct targets. Axons often follow very precise paths in the nervous system, and how they manage to find their way so accurately is an area of ongoing research.
After being taken up at the synaptic terminal or axon of the target neuron, the rabies virus is enveloped in a vesicle which is transported towards the cell body via axonal dynein. In the wildtype rabies virus, the virus will continue to replicate and spread throughout the central nervous system until it has systemically infected the entire ...
SOX10 is a transcription factor active during embryonic development and abundant evidence indicates that it is essential for the generation of glial lineages from trunk crest cells. [ 8 ] [ 9 ] When SOX10 is inactivated in mice, satellite glia and Schwann cell precursors fail to develop, though neurons are generated normally without issue. [ 8 ]
A synapse during re-uptake. Note that some neurotransmitters are lost and not reabsorbed. Reuptake is the reabsorption of a neurotransmitter by a neurotransmitter transporter located along the plasma membrane of an axon terminal (i.e., the pre-synaptic neuron at a synapse) or glial cell after it has performed its function of transmitting a neural impulse.
Schaffer collaterals are axon collaterals given off by CA3 pyramidal cells in the hippocampus.These collaterals project to area CA1 of the hippocampus [1] and are an integral part of memory formation and the emotional network of the Papez circuit, and of the hippocampal trisynaptic loop.
Neural backpropagation is the phenomenon in which, after the action potential of a neuron creates a voltage spike down the axon (normal propagation), another impulse is generated from the soma and propagates towards the apical portions of the dendritic arbor or dendrites (from which much of the original input current originated).