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Antiplatelet drug. An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation [1] and inhibit thrombus formation. They are effective in the arterial circulation where classical Vitamin K antagonist ...
Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [ 10 ] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent (dual antiplatelet therapy). [ 10 ]
In this three-year study, the addition of vorapaxar to standard of care (aspirin and/or an ADP antagonist such as clopidogrel) significantly reduced the risk of the primary composite endpoint of cardiovascular death, heart attack, stroke, or urgent coronary revascularization by 12 percent compared to placebo plus standard of care. Vorapaxar ...
In the US, ticagrelor is indicated to reduce the risk of stroke in people with acute ischemic stroke or high-risk transient ischemic attack. [5]In the EU, ticagrelor, co-administered with acetylsalicylic acid (aspirin), is indicated for the prevention of atherothrombotic events in adults with acute coronary syndromes or a history of myocardial infarction and a high risk of developing an ...
List of Alone episodes. Alone is an American reality television series on the History channel. The first, second and fourth seasons were filmed on northern Vancouver Island, British Columbia, and the third near Nahuel Huapi National Park in Patagonia, Argentina. It follows the self-documented daily struggles of 10 individuals (7 paired teams in ...
Myocardial infarction (MI) refers to tissue death (infarction) of the heart muscle (myocardium) caused by ischemia, the lack of oxygen delivery to myocardial tissue. It is a type of acute coronary syndrome, which describes a sudden or short-term change in symptoms related to blood flow to the heart. [ 22 ]
Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [ 1 ] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [ 2 ]
Alone. (TV series) Alone is an American survival competition series on History. It follows the self-documented daily struggles of 10 individuals (seven paired teams in season 4) as they survive alone in the wilderness for as long as possible using a limited amount of survival equipment. With the exception of medical check-ins, the participants ...