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Medicinal or pharmaceutical chemistry is a scientific discipline at the intersection of chemistry and pharmacy involved with designing and developing pharmaceutical drugs. Medicinal chemistry involves the identification, synthesis and development of new chemical entities suitable for therapeutic use. It also includes the study of existing drugs ...
ACS Medicinal Chemistry Letters is a monthly peer-reviewed scientific journal covering medicinal chemistry. It was established in 2009 and is published by the American Chemical Society. The editor-in-chief is Dennis C. Liotta (Emory University). According to the Journal Citation Reports, the journal has a 2021 impact factor of 4.632.
Schematic structure of an antibody–drug conjugate (ADC) Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. [1] Unlike chemotherapy, ADCs are intended to target and kill tumor cells while sparing healthy cells. As of 2019, some 56 pharmaceutical companies were ...
Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in South Boston, Massachusetts, and three research facilities, in San Diego ...
Stiefel Laboratories Inc. is an American dermatological pharmaceutical company, with its global headquarters in Research Triangle Park, North Carolina. [1] It makes products such as Duac and Oilatum. [2] Stiefel was acquired by GSK plc at a price of $2.9 billion. [3][4] The company was founded in 1847 by John David Stiefel, who initially ...
Bristol-Myers Squibb's shares traded at over $55 per share, and its market capitalization was valued at over US$81.6 billion in October 2018. [ 91 ] In 2018, 85% of the company's revenues came from just five products. [ 92 ] In 2018, Bristol-Myers Squibb spent 36% of its total revenue on R&D expenses. [ 93 ]
The European Journal of Medicinal Chemistry is a monthly peer-reviewed scientific journal covering medicinal chemistry and published by Elsevier. It was established in 1966 as Chimica Therapeutica (CODEN: CHTPBA) and obtained its current title in 1974. From 1974 to 1981 the journal was still subtitled as Chimica Therapeutica and from 1982 to ...
Contents. Amgen. Amgen Inc. (formerly Applied Molecular Genetics Inc.) is an American multinational biopharmaceutical company headquartered in Thousand Oaks, California. [ 3 ][ 4 ] One of the world's largest independent biotechnology companies, As of 2022, Amgen has approximately 24,000 staff in total. [ 5 ] The name "AMGen" is a portmanteau of ...