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The main walls of the heart are formed between day 27 and 37 of the development of the early embryo. The growth consists of two tissue masses actively growing that approach one another until they merge and split light into two separate conduits. Tissue masses called endocardial cushions develop into atrioventricular and conotruncal regions. In ...
The heart is located in the middle of the abdomen with its tip slightly towards the left side of the abdomen. Disorders of the heart lead to heart disease and cardiovascular disease and can lead to a significant number of deaths: cardiovascular disease is the leading cause of death in the U.S. and caused 24.95% of total deaths in 2008. [19]
Genes. Frequency. 0.01%. Situs inversus (also called situs transversus or oppositus) is a congenital condition in which the major visceral organs are reversed or mirrored from their normal positions. The normal arrangement of internal organs is known as situs solitus. Although cardiac problems are more common, many people with situs inversus ...
Fibrillin-1 is a protein that in humans is encoded by the FBN1 gene, located on chromosome 15. [ 5 ][ 6 ] It is a large, extracellular matrix glycoprotein that serves as a structural component of 10–12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue ...
In 2010, for the first time, the genes responsible for the unique adaptive traits were identified following genome sequencing of 50 Tibetans and 40 Han Chinese from Beijing. Initially, the strongest signal of natural selection was a transcription factor involved in response to hypoxia, called endothelial Per-Arnt-Sim (PAS) domain protein 1 .
Human genetics is the study of inheritance as it occurs in human beings. Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population genetics, developmental genetics, clinical genetics, and genetic counseling.
Gene–environment interaction occurs when genetic factors and environmental factors interact to produce an outcome that cannot be explained by either factor alone. [6] For example, a study found that individuals carrying the genetic variant 5-HTT (the short copy) that encodes the serotonin transporter were at a higher risk of developing depression when exposed to adverse childhood experiences ...
The heart is a muscular organ found in most animals. This organ pumps blood through the blood vessels. [ 1 ] Heart and blood vessels together make the circulatory system. [ 2 ] The pumped blood carries oxygen and nutrients to the tissue, while carrying metabolic waste such as carbon dioxide to the lungs. [ 3 ]