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Most infections show no symptoms, in which case it is known as latent tuberculosis. [1] Around 10% of latent infections progress to active disease that, if left untreated, kill about half of those affected. [1] Typical symptoms of active TB are chronic cough with blood-containing mucus, fever, night sweats, and weight loss. [1]
Other parts of the medical history include prior TB exposure, infection or disease and medical conditions that increase risk for TB disease such as HIV infection. Depending on the sort of patient population surveyed, as few as 20%, or as many as 75% of pulmonary tuberculosis cases may be without symptoms. [2]
Mycobacterium tuberculosis (M. tb), also known as Koch's bacillus, is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. [ 1 ] [ 2 ] First discovered in 1882 by Robert Koch , M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid .
Most people affected by TB do not have symptoms, and the disease is not active. This is called latent tuberculosis. [1] However, about 10% of latent infections progress to active disease, which, if left untreated, kills about half of those affected. [1]
It’s estimated that about two billion people worldwide are infected with mycobacterium tuberculosis, often just shortened to tuberculosis or simply ‘TB’. Two billion is a ton of people, but even though they’re infected, that doesn’t mean all those people have symptoms, the vast majority, about 90-95%, aren’t even aware they’re ...
Multidrug resistant tuberculosis poses a threat to people with Pott's disease, making it difficult to determine infection in people because of the paucibacillary symptoms of the disease. Cases of tuberculosis have been on the decline; however, infections of multidrug resistant tuberculosis have remained constant since the 1990s.
Miliary tuberculosis is a form of tuberculosis that is characterized by a wide dissemination into the human body and by the tiny size of the lesions (1–5 mm). Its name comes from a distinctive pattern seen on a chest radiograph of many tiny spots distributed throughout the lung fields with the appearance similar to millet seeds—thus the term "miliary" tuberculosis.
In 2008, evidence for tuberculosis infection was discovered in human remains from the Neolithic era dating from 9,000 years ago, in Atlit Yam, a settlement in the eastern Mediterranean. [7] This finding was confirmed by morphological and molecular methods; to date it is the oldest evidence of tuberculosis infection in humans.