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  2. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Unique to each opioid is its distinct binding affinity to the various classes of opioid receptors (e.g. the μ, κ, and δ opioid receptors are activated at different magnitudes according to the specific receptor binding affinities of the opioid). For example, the opiate alkaloid morphine exhibits high-affinity binding to the μ-opioid receptor ...

  3. Opiate - Wikipedia

    en.wikipedia.org/wiki/Opiate

    The remaining 30% of opioid receptors are located post-synaptically on dendrites of second-order spinothalamic neurons & interneurons. [36] When an opiate binds as an agonist to the GPCR, there will be a signaling cascade resulting in the inhibition of adenylate cyclase and calcium ion channels with the stimulation of potassium ion channels.

  4. List of opioids - Wikipedia

    en.wikipedia.org/wiki/List_of_opioids

    Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."

  5. Category:Opioids - Wikipedia

    en.wikipedia.org/wiki/Category:Opioids

    Opioid agonist therapy; Opioid excess theory; Opioid food peptides; Opioid overdose; Opioid rotation; Opioid withdrawal; Opioid-induced endocrinopathy; Opioid-induced hyperalgesia; Opioidergic; Opioids and pregnancy; Opium; Oxycodone; Oxymorphone-3-methoxynaltrexonazine

  6. Utopioid (drug class) - Wikipedia

    en.wikipedia.org/wiki/Utopioid_(drug_class)

    Following the prohibition of U-47700, a number of related compounds have continued to appear on illicit drug markets. They are often marketed online or included as components in mixtures sold under the guise of "street heroin." U-47700 itself is the most potent mu opioid agonist from this class, around 7-10x the potency of morphine.

  7. Prescription drug addiction - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_Addiction

    Prescription drug addiction is the chronic, repeated use of a prescription drug in ways other than prescribed for, including using someone else’s prescription. [3] [4] A prescription drug is a pharmaceutical drug that may not be dispensed without a legal medical prescription.

  8. List of benzimidazole opioids - Wikipedia

    en.wikipedia.org/wiki/List_of_benzimidazole_opioids

    The structure-activity relationship of the drug class has been explored to a reasonable extent. The optimal substitution pattern is fairly tightly defined (i.e. N,N-diethyl on the amine nitrogen, 4-ethoxy on the benzyl ring and 5-nitro on the benzimidazole ring), but even derivatives incorporating only some of these features are still potent opioids.

  9. Addiction - Wikipedia

    en.wikipedia.org/wiki/Addiction

    In contemporary modern English "-holic" is a suffix that can be added to a subject to denote an addiction to it. It was extracted from the word alcoholism (one of the first addictions to be widely identified both medically and socially) (correctly the root " alcohol " plus the suffix "-ism") by misdividing or rebracketing it into "alco" and ...

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