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Treatment for CMV infection should start at 1 month of age and should occur for 6 months. The options for treatment are intravenous ganciclovir and oral valganciclovir. After diagnosis, it is important to further investigate any possible evidence of end-organ disease and symptoms through blood tests, imaging, ophthalmology tests, and hearing tests.
Most commonly, valganciclovir or ganciclovir are used as first-line antiviral therapy for congenital CMV. [11] If the cause is a malignancy, the patient should receive cancer treatment such as chemotherapy. [6] Overall, treatment of the blueberry muffin baby is centered around the underlying cause.
The CMV pp65 assay is widely used for monitoring CMV infection and its response to antiviral treatment in people who are under immunosuppressive therapy and have had renal transplantation surgery, as the antigenemia results are obtained about 5 days before the onset of symptomatic CMV disease.
Cytomegalovirus (CMV) (from cyto-'cell' via Greek κύτος kútos - 'container' + μέγας mégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, [3] in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts.
Before delivery treatment of the mother with antibiotics reduces the rate of neonatal infection. [31] Prevention of the infection of the baby is done by treating the mother with penicillin. Since the adoption of this prophylactic treatment, infant mortality from GBS infection has decreased by 80%. [36]
Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness. [1] Caused by human cytomegalovirus , it occurs predominantly in people whose immune system has been compromised, including 15-40% of those with AIDS.
Signs include vomiting, diarrhea, collapse, difficulty breathing, and body temperature approaching 42 °C to 43 °C. Treatment includes cooling the dogs with wet towels and fans, intravenous fluid therapy, and other supportive care. [171] If a dog's temperature begins to drop to around 40 °C, stop the cooling process.
CMV colitis may be clinically manifested with diarrhea (usually non-bloody), abdominal pain, weight loss and anorexia. The diagnosis of CMV colitis is based on serology, CMV antigen testing and colonoscopy with biopsy. Clinical suspicion should be aroused in the setting of immunocompromised patient but it is much rarer in immunocompetent patient.